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Ac-Endothelin-1 (16-21), human

Ac-Endothelin-1 (16-21), human
ENDOTHELIN-1 (ET-1), the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly conserved sequence in the peptides of the ET family, has been shown to discriminate between the two ET receptor subtypes termed ETA and ETB since it activates only the latter ones.
Catalog No. T22540
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Ac-Endothelin-1 (16-21), human

Catalog No. T22540
ENDOTHELIN-1 (ET-1), the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly conserved sequence in the peptides of the ET family, has been shown to discriminate between the two ET receptor subtypes termed ETA and ETB since it activates only the latter ones.
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5 mg$87Backorder
10 mg$143Backorder
25 mg$198Backorder
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Product Introduction

Bioactivity
Description
ENDOTHELIN-1 (ET-1), the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly conserved sequence in the peptides of t
In vitro
At the cellular level, the effects of ET-1 appear to be mediated by two speci?c receptor subtypes termed ETA and ETB, both of which are functionally coupled to phospholipase C (PLC).
Chemical Properties
Molecular Weight837.96
FormulaC41H59N9O10
Cas No.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: > 83.8 mg/mL, Heating is recommended.

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